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Showing posts with label East Asian. Show all posts
Showing posts with label East Asian. Show all posts

October 6, 2013

Understanding Your DNA Results: Comparison Charts

DNA is the latest genealogy tool and I've had my DNA tested with 3 different companies now (with one more pending). I used Family Tree DNA, 23andMe.com and DNA-me for testing. Since I'm a woman I can only test my Mt-DNA or my Autosomal. I have to leave the Y-DNA tests to a male relative. 

DNA results are not easy to understand and I don't pretend to understand them very well at all. So what I have done is make a spreadsheet of the summary of my DNA results - the Haplogroup I am in, my genetic origins and my percentages of various ethnicities. 

Each test is likely to show different results depending on the number of markers that were tested and the algorithms used to interpret the test. So I expected to find some differences but that is what makes testing with more than one company worthwhile. In fact it's important if you want to understand your DNA in more depth.

Definitions

You also have to do a lot of reading (aka research) to increase your knowledge of DNA testing, the various tests and what the results mean. What I have gleaned (admititily just the tip of the DNA iceberg!) Is this: 

MtDNA - Maternal DNA is passed from mother to child (of either sex) and does not change over the generations. A female testing her MtDNA is testing her female lineage from herself to her mother to her mother's mother and so on. This is the X chromosome

Y-DNA - Paternal DNA tests the Y chromosome which is passed, unchanged, from father to son. Thus if you wish to test for your surname and you are a woman, you must find a male relative with that surname to take the test. Women do not have the Y chromosome (We are XX while men are XY)

Autosomal: Autosomal DNA recombines with every generation and that means the number of markers you share with a common ancestor is halved with each generation. 

Haplogroups: The Haplogroup your DNA indicates you belong to will show your deep roots, your heritage going back thousands of years.  

This is very basic but it's a start to understanding. There's no sense paying money for DNA tests and then just letting the results sit there because you don't understand what was tested or what the results mean.




My DNA Test Results

Here is the chart I've finished which shows the comparison of the 3 companies whose results are in. My 4th company is still running my DNA samples so I don't have that yet.


Family Tree DNA is the one marked as FT DNA. They do not narrow down my ethnic origins as much as 23andMe.com but you can see that they both agree the majority of my ethnic origins are European of some sort. 

DNA-me is the surprise with their finding of a smidgeon of African origin. And their Haplogroup assignment of JT also throws me a bit. I have more research to do to try to understand how that happened. I am pretty sure they didn't test very many markers and the more markers tested, the  more accurate the results.

You can also see that 23andMe.com has both Standard (75% accuracy) and Speculative (50% accuracy) results so I included them. The East Asian was interesting especially when I compared my test results to my brother's. Since his tests include the full Y chromosome testing there are bound to be some differences. And I love that 23andMe.com tests for your percentage of Neanderthal ancestry in your DNA! 

My Brother's DNA Results

For example even though we know we have Native American heritage on my father's side, it does not show on my results with any company. But it does show on my brother's results through 23andMe (but not Family Tree DNA) and on tests that Professor McDonald ran on my brother's Family Tree DNA raw data. Again this points out the importance of testing with more than one company. 



You can see that testing my brother's DNA confirmed our Native American heritage and the Asian heritage shown for me in both 23andMe and DNA-me testing. The big surprise was the Ashkenazi in his speculative results. It's important though to note that these results are only considered to have 50% accuracy. They may be correct but they are equally likely to be wrong. 

DNA Matches

I've also been studying and reading about how to compare raw data with matches found for me in each of the DNA company's databases. I'm getting better and can now narrow down the ethnicity we share (based on what chromosomes we match on). This obviously helps with figuring out who our common ancestor might be, but I have much more to learn. When I have that a bit more figured out I will post here. 

Meantime if there are any readers who understand what I've posted today better than I do (or better than my explanation) please do leave a comment so we can all learn from each other's knowledge.  

April 3, 2013

DNA Results Showing Native American and East Asian Heritage

My  23andMe.com Ancestry results came in last week. I was fascinated by the sub-regional breakdown of my lineage. The chart above shows that I have 18% British and Irish, 1.4% French and German, 71.7% non-specific Northern European, 8.7% non-specific European, .1% East Asian and the rest unspecified.

What surprised me was no Native American showing for me (it is confirmed that I have Native American heritage through a Mohawk ancestor, Ots-Toch born ca 1622 in what is now New York state), and that I have a small bit of East Asian.  However it's important to note that one test isn't the final answer, especially when searching for confirmation of heritage from several generations back.

So it doesn't concern me at all that my Native American heritage doesn't show in the  23andMe.com results. The raw data from my brother's DNA test on Family Tree DNA also did not show our Native American heritage until I had it analyzed by Professor MacDonald, who is conducting his own study on DNA and has a different set of algorithms for providing results.  Then it showed my brother as having .7% Native American heritage.

And the icing on the cake is that my brother's DNA test from  23andMe.com also showed our Native American heritage at .7% (with East Asian at .1% just as mine is)


My brother's test from 23andMe also showed .7% Iberian which is the region of Spain and surrounding areas. We know from his raw data that he has a rare mutation which is known to have occurred when a group of Basque men went up to help build Hadrian's Wall between Scotland and England.  So that fits with the finding of Iberian heritage.

I still have a lot of reading to do to fully understand my DNA results (and my brother's) but it is an exciting and interesting adventure!